Perioperative Use of Colloids

Perioperative use of methotrexate.

Methotrexate (MTX) is the disease modifying antirheumatic 'anchor' drug for the treatment of patients with rheumatoid arthritis (RA). Despite its widespread use and the frequent need of elective orthopaedic and other types of surgical procedures in patients with RA, some confusion exists concerning the use of MTX in the perioperative period. Currently available data do not suggest a need to dis...

The use of colloids in clinical practice.

The use of colloid solutions for fluid resuscitation in hypovolaemic patients is widespread in clinical practice. This article describes the types of colloid agents which are currently available, their physicochemical properties, and adverse effects which may follow their administration. The relative merits of colloids compared with crystalloid solutions are discussed.

Perioperative melatonin use.

Melatonin is a substance chiefly produced by the pineal gland and has a key role in the sleep-wake cycle. It also has an important antioxidant role. Exogenous melatonin has a short half-life and is available in a range of preparations. Newer analogues targeted for the recently discovered melatonin MT1 and MT2 receptors have also been developed. Exogenous melatonin is used as a resynchronisation...

Perioperative use of beta-blockers

Perioperative beta-blocker therapy has been considered a mainstay of perioperative cardioprotection in patients with or at risk of coronary artery diseases. However, current recommendations for perioperative beta blockade are based mainly on the findings of trials with inadequate methodology and data analysis. The recently published results of the first adequately powered large controlled rando...

Perioperative Use of Intravenous Lidocaine.